LEMTRADA is a prescription medicine used to treat adults with relapsing forms of multiple sclerosis (MS). Because of its risks, LEMTRADA is generally used in people who have tried 2 or more MS medicines that have not worked well enough. It is not known if LEMTRADA is safe and effective for use in children under 17 years of age.


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LEMTRADA is a prescription medicine used to treat adults with relapsing forms of multiple sclerosis (MS). Because of its risks, LEMTRADA is generally used in people who have tried 2 or more MS medicines that have not worked well enough. It is not known if LEMTRADA is safe and effective in children under 17 years of age.

How do I take LEMTRADA?

LEMTRADA is given through a needle placed in your vein (IV infusion). When starting LEMTRADA, you will receive 8 infusions over two years—on 5 consecutive days in round 1 and, one year later, on 3 consecutive days in round 2. You and your healthcare provider may decide that you need one or more additional rounds of treatment. If so, this would occur at least 1 year after your last round and would consist of 3 treatment days in a row.

How long does each infusion last?

Each infusion takes approximately 4 hours. Afterward, your healthcare provider will monitor you for at least 2 hours for infusion reactions. The total time you spend at the infusion facility will depend on how your body reacts to the infusion. Your healthcare provider will let you know when you are ready to go home for the day. Infusion reactions, though, may happen up to 24 hours or longer after you've received LEMTRADA.

What kind of side effects can happen during an infusion?

Some of the common infusion reactions for patients who receive LEMTRADA included nausea, hives, itching, difficulty sleeping, chills, flushing, fatigue, shortness of breath, congestion of the lungs, upset stomach, dizziness, and pain.

Some serious reactions are also possible, such as life-threatening allergic reactions, swelling, wheezing, low blood pressure, chest pain, a fast, slow, or irregular heartbeat, transient neurologic symptoms, high blood pressure, headache, fever, and rash. In addition, some people have had serious and sometimes deadly strokes and tears in their arteries that supply blood to the brain. To learn more, please click here to read the Medication Guide.

How do I arrange my lab monitoring tests?

The LEMTRADA Central Lab Program offers a variety of ways you can get your blood and urine tests done at no cost to you. Options include going to a local LabCorp or Quest Diagnostics patient service center or having a lab technician come to your home. You can also have the tests completed at your healthcare provider's office. If samples are taken at your healthcare provider's office, you may have to pay a co-pay. However, the cost of analyzing the samples will still be covered by the LEMTRADA Central Lab Program. You should talk to your healthcare provider and MS One to One® Nurse about which option works best for you.

Is there financial assistance available?

Eligible* patients enrolled in the LEMTRADA Co-Pay Program receive LEMTRADA at $0 out-of-pocket cost and up to $100 for each day of infusion toward the cost of infusion administration (commercially insured residents of Massachusetts, Minnesota, Michigan, and Rhode Island are not eligible for infusion-related financial assistance). To learn more, please call MS One to One at 1‑855‑676‑6326 1‑855‑676‑6326.

Are there any medications I should avoid while on LEMTRADA?

You should talk to your doctor before taking any prescription medication, over-the-counter medicines, vitamins, and herbal supplements. Tell your healthcare provider if you take medicines that increase your chance of getting infections, including medicines used to treat cancer or to control your immune system. Keep a list of all of your medications to show to your healthcare provider.

Is it okay if I get pregnant while taking LEMTRADA?

You should talk to your doctor if you plan to become pregnant. LEMTRADA may harm your unborn baby. You should use birth control while receiving LEMTRADA and for 4 months after your course of treatment.

What if I still have questions about LEMTRADA?

Talk to your doctor if you have questions about LEMTRADA. In addition, MS One to One was developed to assist those living with relapsing MS and their Care Partners throughout their MS journey, from diagnosis to daily management and everything in between. By enrolling in this program, you will be assigned a specialized MS Nurse who can give you and your loved ones customized support, facts regarding your treatment and potential side effects, and educational MS resources. To learn more, please call the MS One to One hotline at 1‑855‑676‑6326 1‑855‑676‑6326.

*Patients who have coverage or prescriptions paid for in part or in full under Medicare, Medicaid, or other state or federally funded healthcare programs are not eligible. The LEMTRADA Co-Pay Program is subject to termination or modification at any time. Depending on your specific situation, your MS One to One Nurse can direct you to other patient assistance programs that may offer you financial support.

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